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  • Autism (64)
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    • Autism Spectrum Disorders – I (Neurotypical Brain versus Autistic Brain) (8)
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Proton Power: Life’s Molecular Drive for Energy
Mitochondria (In Health and Disease)

Proton Power: Life’s Molecular Drive for Energy

Explore how proton gradients power life’s energy, from ATP synthesis to cellular transport—unraveling the elegant science behind bioenergetics.

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Folate and Vitamin B12 (In Health and Disease) Folate Contents of Foods Naturally Occurring Food Folates
Folate and Vitamin B12 (In Health and Disease)

Folate in Health and Disease: Folate Concentrations in Serum, Whole Blood, and Cerebrospinal Fluid

Discover folate sources, bioavailability, and concentrations in serum, whole blood, and CSF. Learn about folate’s role in health and its impact on various age groups.

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Neurodiversity & Wellbeing What is the link between Autism and the Alzheimer's Disease?
Neurodiversity & Wellbeing

What is the link between Autism and the Alzheimer’s Disease?

Discover the intriguing connection between autism and Alzheimer’s disease, exploring genetic links, brain changes, immune dysfunction, early life factors, and the role of folate in both conditions.

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Autism Exploring Common Comorbidities in Autism
Autism

Exploring Common Comorbidities in Autism

Explore common comorbidities in autism, from mental health disorders to genetic conditions. Learn more about prevalence, treatment, and the importance of early intervention.

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Neurodiversity & Wellbeing What is the Link between Folate, FRAAs, and Depression?
Neurodiversity & Wellbeing

What is the Link between Folate, FRAAs, and Depression?

Discover the link between folate, depression, and folate receptor autoantibodies. Learn how folate deficiency impacts mental health and potential treatments.

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Folate and Vitamin B12 (In Health and Disease) Folate Metabolism Related Enzymes Transporters Folate Mediated One Carbon 1 C Metabolism Blog Listing Image
Folate and Vitamin B12 (In Health and Disease)

Folate in Health and Disease: Genetic Defects in Folate Pathway Influencing the Central Nervous System

Explore the role of folate in brain health & neurological disorders. Learn more about genetic defects impacting folate metabolism & potential treatments.

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Neurodiversity & Wellbeing Is Folate (Vitamin B9) Important for Mental Health?
Neurodiversity & Wellbeing

Is Folate (Vitamin B9) Important for Mental Health?

Discover the vital role of folate in adult health and its impact on conditions like anemia and heart disease. Learn more about FRAAs and their implications for mental well-being.

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Autism What is PANS and What is PANDAS?
Autism

PANS/PANDAS – Symptoms, Diagnosis, Treatment, & New Research

Learn more about PANS/PANDAS, pediatric neuropsychiatric disorders, symptoms, diagnosis, treatment options, and promising research findings on folate receptor autoantibodies.

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Neurodiversity & Wellbeing Why is Folate Important for Young Adults?
Neurodiversity & Wellbeing

Why is Folate Important for Young Adults?

Discover the vital role of folate (vitamin B9) in health. Learn about sources, benefits, and risks of deficiency in young adults. Stay informed for better well-being.

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Autism What is Asperger’s Syndrome?
Autism

What is Asperger’s Syndrome?

Learn more about Asperger’s Syndrome history, symptoms, and differences from autism. Understand the transition to ASD and the importance of seeking professional evaluation.

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Neurodiversity & Wellbeing What Role Do Folate and Folate Receptor Autoantibodies Play in Adolescence?
Neurodiversity & Wellbeing

What Role Do Folate and Folate Receptor Autoantibodies Play in Adolescence?

Folate plays a vital role in teens physical and mental health. Explore how deficiencies impact neurological well-being during adolescence.

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Neurodiversity & Wellbeing What is the role of Vitamin B9 variants in Child Development and their link to ASD?
Neurodiversity & Wellbeing

What is the role of Vitamin B9 variants in Child Development and their link to ASD?

Learn about folate, vitamin B9, and child development, including their role in preventing neural tube defects and potential impact on ASD.

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Folate and Vitamin B12 (In Health and Disease) What makes cobalamin (Vitamin B12) nature's most beautiful cofactor?
Folate and Vitamin B12 (In Health and Disease)

Vitamin B12 in Health and Disease: Biochemistry, Metabolic Function, and Transport of Cobalamin

Explore the biochemistry and metabolic functions of Vitamin B12 (cobalamin) in health and disease.

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Neurodiversity & Wellbeing What is driving the recent increase in ASD diagnoses? Reflections during Autism Awareness Month
Neurodiversity & Wellbeing

What is driving the recent increase in ASD diagnoses? Reflections during Autism Awareness Month

Discover the factors contributing to the rise in autism diagnoses, from increased awareness to genetic and environmental influences. Join us for Autism Awareness Month!

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Autism
Autism

Understanding ABA Therapy: A Key to Unlocking Potential in Children with Autism

Discover the benefits of ABA therapy for children with autism. Learn how it helps manage behaviors, develop skills, and improve communication.

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Neurodiversity & Wellbeing What role does folate play in young children, and what are the consequences of CFDS?
Neurodiversity & Wellbeing

What role does folate play in young children, and what are the consequences of CFDS?

Discover the essential role of folate in brain health. Learn more about its functions, deficiency risks, and potential treatments for neurological symptoms.

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  • FRAT® (Folate Receptor Antibody Test) is a diagnostic blood test that screens for Folate Receptor Autoantibodies. Developed in the laboratory of Dr. Edward Quadros at the State University of New York (SUNY Downstate), FRAT® is the only assay that identifies BOTH blocking and binding Folate Receptor Autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world's leading assay of its kind.

    The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into the cerebrospinal fluid (CSF).

    Folate Receptor Autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Depression, Schizophrenia as well as other neuropsychiatric and neurodevelopmental disorders.

    Diagnosis of Folate Receptor Autoantibodies should be done as early as possible as this may affect treatment outcomes.

    Please consult your physician for further information.

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