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  • Autism (66)
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  • FRAT (1)
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Folate and Depression – What is the Connection?
Neurodiversity & Wellbeing

Folate and Depression – What is the Connection?

Discover how folate impacts brain function, neurotransmitters, and inflammation—uncover its powerful role in preventing and managing depression.

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Autism Why ABA Therapy Doesn’t Work?
Autism

Why ABA Therapy Doesn’t Work?

Discover why ABA therapy might not work for everyone, exploring known limitations and emerging factors like cerebral folate deficiency affecting autism treatment.

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Neurodiversity & Wellbeing Making Friends with an Autistic Child
Neurodiversity & Wellbeing

Making Friends with an Autistic Child

Learn how parents can help their children befriend autistic children, fostering understanding and inclusivity in school-age friendships.

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Developmental Origins of Health and Disease (DOHaD) Epigenetic Remodeling in Embryogenesis
Developmental Origins of Health and Disease (DOHaD)

Developmental Origins of Health and Disease: Epigenetics, Nutrition, and Infant Health

Explore how epigenetics and nutrition impact infant health and development, influencing lifelong well-being through mechanisms like DNA methylation and histone modification.

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Neurodiversity & Wellbeing Folate Receptor Autoantibodies – Be Aware!
Neurodiversity & Wellbeing

Folate Receptor Autoantibodies – Be Aware !

Discover the impact of Folate Receptor Autoantibodies (FRαa) on health, affecting folate transport to the brain. Learn about diagnosis, treatment, and implications for neurodevelopmental disorders.

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Autism
Autism

Frequently Asked Questions on ADHD & Autism Overlap, Differences

Confused about ADHD and Autism? This blog clears up the confusion, explains the differences, and answers the most frequently asked questions on ADHD and Autism.

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Neurodiversity & Wellbeing What is the link between Brain Plasticity, Folate, and FRAAs?
Neurodiversity & Wellbeing

What is the link between Brain Plasticity, Folate, and FRAAs?

Discover how early brain plasticity influences cognition and the critical roles of folate and FRAAs in brain development. Learn about the FRAT® test for assessing folate receptor autoantibodies.

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Developmental Delays (In Infancy and Early Childhood) Tetrahydrofolate THF and Tetrahydrobiopterin-BH4
Developmental Delays (In Infancy and Early Childhood)

Developmental Delays in Infancy and Early Childhood: Biopterin and Folate Metabolism Interrelations

Uncover the link between biopterin and folate metabolism in developmental delays. Explore BH4 deficiency, its impact on neurotransmitters, and potential treatments for ASD and other conditions.

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Neurodiversity & Wellbeing Autism, Infertility, Developmental Delays: Can the FRAT® Test Help?
Neurodiversity & Wellbeing

FRAT® (Folate Receptor Autoantibody Test) and its Urgency.

Concerned about unexplained health issues in your child? Learn how the FRAT® Test can identify Folate deficiencies and support a personalized treatment plan.

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Autism Clothing Sensitivity in Autism
Autism

Clothing Sensitivity in Autism

Explore the reasons behind clothing sensitivity in autism and the impact it has on daily life. Discover strategies for creating a comfortable wardrobe and addressing public undressing.

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Neurodiversity & Wellbeing What is FRAT®?
Neurodiversity & Wellbeing

What is FRAT®?

FRAT® (Folate Receptor Autoantibody Test) detects autoantibodies against folate receptors, helping diagnose neurological disorders, pregnancy complications, and cerebral folate deficiency.

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Folate and Vitamin B12 (In Health and Disease) Folate Contents of Foods Naturally Occurring Food Folates
Folate and Vitamin B12 (In Health and Disease)

Folate in Health and Disease: Folate Concentrations in Serum, Whole Blood, and Cerebrospinal Fluid

Discover folate sources, bioavailability, and concentrations in serum, whole blood, and CSF. Learn about folate’s role in health and its impact on various age groups.

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Neurodiversity & Wellbeing What is the link between Autism and the Alzheimer's Disease?
Neurodiversity & Wellbeing

What is the link between Autism and the Alzheimer’s Disease?

Discover the intriguing connection between autism and Alzheimer’s disease, exploring genetic links, brain changes, immune dysfunction, early life factors, and the role of folate in both conditions.

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Autism Exploring Common Comorbidities in Autism
Autism

Exploring Common Comorbidities in Autism

Explore common comorbidities in autism, from mental health disorders to genetic conditions. Learn more about prevalence, treatment, and the importance of early intervention.

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Neurodiversity & Wellbeing What is the Link between Folate, FRAAs, and Depression?
Neurodiversity & Wellbeing

What is the Link between Folate, FRAAs, and Depression?

Discover the link between folate, depression, and folate receptor autoantibodies. Learn how folate deficiency impacts mental health and potential treatments.

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Folate and Vitamin B12 (In Health and Disease) Folate Metabolism Related Enzymes Transporters Folate Mediated One Carbon 1 C Metabolism Blog Listing Image
Folate and Vitamin B12 (In Health and Disease)

Folate in Health and Disease: Genetic Defects in Folate Pathway Influencing the Central Nervous System

Explore the role of folate in brain health & neurological disorders. Learn more about genetic defects impacting folate metabolism & potential treatments.

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  • FRAT® (Folate Receptor Antibody Test) is a diagnostic blood test that screens for Folate Receptor Autoantibodies. Developed in the laboratory of Dr. Edward Quadros at the State University of New York (SUNY Downstate), FRAT® is the only assay that identifies BOTH blocking and binding Folate Receptor Autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world's leading assay of its kind.

    The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into the cerebrospinal fluid (CSF).

    Folate Receptor Autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Depression, Schizophrenia as well as other neuropsychiatric and neurodevelopmental disorders.

    Diagnosis of Folate Receptor Autoantibodies should be done as early as possible as this may affect treatment outcomes.

    Please consult your physician for further information.

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