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  • Autism (64)
  • Diagnosis & Therapy (10)
  • FRAT (1)
  • Neurodiversity & Wellbeing (74)
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  • Science (44)
    • Autism Spectrum Disorders – I (Neurotypical Brain versus Autistic Brain) (8)
    • Autism Spectrum Disorders – II (Comorbid Mental Health Problems) (7)
    • Brain and Mind Development (First 5 Years of Life) (3)
    • Developmental Delays (In Infancy and Early Childhood) (5)
    • Developmental Origins of Health and Disease (DOHaD) (5)
    • First 1000 Days (From Conception to 2 years of Age) (3)
    • Folate and Vitamin B12 (In Health and Disease) (9)
    • Microbiome (In Health and Disease) (5)
    • Mitochondria (In Health and Disease) (3)
    • Nutrition (In Health and Disease) (1)
  • Signs & Symptoms (7)
Folate. Autism. Depression What’s the Link?
Neurodiversity & Wellbeing

Folate. Autism. Depression What’s the Link?

Explore how folate impacts brain health and its link to depression and autism, including MTHFR mutations, FRAAs, and potential treatment strategies.

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Autism Calming Strategies for Children with Autism
Autism

Calming Strategies for Children with Autism

Discover effective calming strategies to help your child with autism manage stress, anxiety, and sensory overload. Learn about sensory-based techniques, breathing exercises, mindfulness, and more.

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Neurodiversity & Wellbeing Folinic Acid and ASD: Unveiling the Potential in Pediatric Neurodevelopment
Neurodiversity & Wellbeing

Folinic Acid and ASD: Unveiling the Potential in Pediatric Neurodevelopment

Explore how folinic acid could improve speech and behaviors in children with autism linked to folate deficiency. Learn more about testing and early intervention benefits.

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Developmental Origins of Health and Disease (DOHaD) Development of Gut Microbiome from Infancy to Childhood Diversity Increases from Day 0 to Day 1,000 of Life
Developmental Origins of Health and Disease (DOHaD)

Developmental Origins of Health and Disease: Transition from Infant to Child Microbiome ~ Day 365 to 1,000 and Beyond

Explore the transition from infant to child gut microbiome, its stabilization, key influencing factors, and its impact on long-term health in the first 1,000 days.

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Neurodiversity & Wellbeing
Neurodiversity & Wellbeing

A Healthy Diet during Pregnancy May Lower the Risk of Childhood Autism

Explore how a healthy prenatal diet rich in essential nutrients can support fetal brain development and potentially lower the risk of autism in children.

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Autism The Importance Of Play Therapy In Autism
Autism

The Importance Of Play Therapy In Autism

Discover the power of play therapy in helping children with autism thrive. Learn about its benefits, techniques, and how it can be combined with other therapies for optimal outcomes.

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Neurodiversity & Wellbeing Folate Receptor Autoantibodies in Autism Spectrum Disorders
Neurodiversity & Wellbeing

Folate Receptor Autoantibodies in Autism Spectrum Disorders

Discover how folate receptor autoantibodies impact neurodevelopment and autism, and explore treatments like high-dose folinic acid for positive outcomes.

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Autism The Importance of Vitamin B9 (Folate), Folate Metabolism and Folate Transport
Autism

The Importance of Vitamin B9 (Folate), Folate Metabolism and Folate Transport

Discover the crucial role of Vitamin B9 (Folate) in brain health, DNA synthesis, and preventing birth defects. Learn more about folate transport, metabolism, and managing deficiencies.

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Neurodiversity & Wellbeing Autism and Toilet Training
Neurodiversity & Wellbeing

Autism and Toilet Training

Toilet training a child with autism? Discover tips on readiness, routines, positive reinforcement, sensory considerations, and more for a smoother, more successful process.

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Autism
Autism

Bedwetting And Autism: Understanding The Connection And Possible Folate Link

Discover the link between bedwetting and autism. Find out how folate and vitamin B12 deficiencies might be connected to this issue. Learn about potential causes, treatment options, and how to support your child.

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Neurodiversity & Wellbeing Vitamin B9, It’s importance and relevance in Autism
Neurodiversity & Wellbeing

Vitamin B9, It’s importance and relevance in Autism

Discover the essential role of Vitamin B9 in autism, including the impact of folate receptor autoantibodies and promising treatments with high-dose folinic acid.

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Developmental Origins of Health and Disease (DOHaD) Neonatal Microbiome Breastfed Infants Versus Formula Fed Infants
Developmental Origins of Health and Disease (DOHaD)

Developmental Origins of Health and Disease: Infant Gut Microbiome ~ Day 31 to 364

Explore the human microbiome’s impact on health, focusing on infant gut development, feeding modes, antibiotics, and the benefits of probiotics and prebiotics.

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Neurodiversity & Wellbeing Autism and Older Fathers – Is there a connection?
Neurodiversity & Wellbeing

Autism and Older Fathers – Is there a connection?

Explore the connection between older fathers and autism risk. Learn about genetic mutations, epigenetic changes, and environmental factors contributing to this link.

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Autism What Can Cause Autism?
Autism

What Can Cause Autism?

Genetic, Environmental, Energy Metabolism, Neurological, Immunological, Nutritional, and Folate: Explore the Potential Causes of Autism Spectrum Disorder.

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Neurodiversity & Wellbeing Autism and Mitochondria
Neurodiversity & Wellbeing

Autism and Mitochondria

Explore the link between mitochondria and autism spectrum disorder (ASD), including their role in energy metabolism, oxidative stress, genetics, and cognitive development.

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Developmental Origins of Health and Disease (DOHaD) Gut Microbiota - Newborns
Developmental Origins of Health and Disease (DOHaD)

Developmental Origins of Health and Disease: Neonatal Gut Microbiome ~ Day 0 to 30

Discover how the neonatal gut microbiome develops from day 0 to 30, shaping immune health and long-term wellness through environmental factors and maternal influences.

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  • FRAT® (Folate Receptor Antibody Test) is a diagnostic blood test that screens for Folate Receptor Autoantibodies. Developed in the laboratory of Dr. Edward Quadros at the State University of New York (SUNY Downstate), FRAT® is the only assay that identifies BOTH blocking and binding Folate Receptor Autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world's leading assay of its kind.

    The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into the cerebrospinal fluid (CSF).

    Folate Receptor Autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Depression, Schizophrenia as well as other neuropsychiatric and neurodevelopmental disorders.

    Diagnosis of Folate Receptor Autoantibodies should be done as early as possible as this may affect treatment outcomes.

    Please consult your physician for further information.

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