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  • Autism (65)
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  • FRAT (1)
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The FRAT® Experience
Neurodiversity & Wellbeing

The FRAT® Experience

Discover the science behind FRAT®—a groundbreaking test linking folate autoantibodies to autism, NTDs, CFD, and more, guiding effective folinic acid therapy.

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Neurodiversity & Wellbeing Why you need the FRAT® test
Neurodiversity & Wellbeing

Why You Need the FRAT® Test?

Discover why the FRAT® test is crucial for detecting folate receptor autoantibodies linked to autism, CFD, and neurological symptoms.

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Mitochondria (In Health and Disease) Cellular Respiration - The Hidden Engine Driving Life's Energy
Mitochondria (In Health and Disease)

Cellular Respiration: The Hidden Engine Driving Life’s Energy

Explore the hidden engine of life—cellular respiration. Discover how glucose, oxygen, and the mitochondrial respiratory chain power every cell through a fascinating journey of energy transformation.

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Neurodiversity & Wellbeing How Folate Receptor Autoantibodies Disrupt Folate Transport at the BBB?
Neurodiversity & Wellbeing

How Folate Receptor Autoantibodies Disrupt Folate Transport at the BBB?

Learn how folate receptor autoantibodies (FRAAs) block folate transport at the BBB, causing cerebral folate deficiency despite normal blood folate levels.

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Neurodiversity & Wellbeing Maternal Autoantibodies and Autism Spectrum Disorders
Neurodiversity & Wellbeing

Maternal autoantibodies and Autism Spectrum Disorders

Discover how maternal autoantibodies may impact fetal brain development and increase autism risk. Learn more about MAR-ASD, key proteins, and emerging research.

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Autism Autism and Down Syndrome: Addressing Common Questions and Misconceptions
Autism

Autism and Down Syndrome: Addressing Common Questions and Misconceptions

Discover key differences and similarities between Autism & Down Syndrome, their causes, symptoms, and co-occurrence.

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Neurodiversity & Wellbeing Autism and Folinic Acid – A New Report by CBS Evening News
Neurodiversity & Wellbeing

Autism and Folinic Acid – A New Report by CBS Evening News

Discover how leucovorin, a folate-based drug, may help speech delays in autism. Learn about research, clinical trials, and parental advocacy for repurposed therapies.

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Neurodiversity & Wellbeing The Relevance of Folate Receptor Autoantibodies to Human Health: An Overview
Neurodiversity & Wellbeing

The Relevance of Folate Receptor Autoantibodies to Human Health: An Overview

Learn about the impact of folate receptor autoantibodies (FRAAs) on health, including NTDs, ASD, cognitive disorders, and potential treatments like folinic acid.

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Autism Spectrum Disorders – II (Comorbid Mental Health Problems) Breaking the Chains of Depression - How Exercise Transforms Minds and Reclaims Lives
Autism Spectrum Disorders – II (Comorbid Mental Health Problems)

Breaking the Chains of Depression: How Exercise Transforms Minds and Reclaims Lives

Discover how exercise transforms mental health! Learn how movement boosts brain function, enhances mood, and combats depression naturally. Take control today!

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Neurodiversity & Wellbeing Early Diagnosis of FRAAs
Neurodiversity & Wellbeing

Early Diagnosis Of FRAAs

Discover how brain plasticity supports learning and recovery, and why early diagnosis of folate receptor autoantibodies (FRAs) is crucial for brain health.

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Autism Touch Aversion in Autism: From Childhood to Adulthood
Autism

Touch Aversion in Autism: From Childhood to Adulthood

Discover the complexities of touch aversion in autism—sensory sensitivity, autonomy, and social context. Learn signs, causes, and practical tips to support autistic children.

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Neurodiversity & Wellbeing Folic Acid - Folinic Acid
Neurodiversity & Wellbeing

Folic Acid – Folinic Acid

Discover the key differences between folic acid & folinic acid, their metabolism, benefits, and why folinic acid may be better for autism & MTHFR mutations.

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Autism Spectrum Disorders – II (Comorbid Mental Health Problems) Navigating Life's Shadows – A Deep Dive into Depression
Autism Spectrum Disorders – II (Comorbid Mental Health Problems)

Navigating Life’s Shadows: A Deep Dive into Depression

Depression affects all ages, from childhood to adulthood. Learn about its symptoms, causes, risk factors, and treatment options for better mental well-being.

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Neurodiversity & Wellbeing Folate Receptor Autoantibodies - Folinic Acid
Neurodiversity & Wellbeing

Folate Receptor Autoantibodies – Folinic Acid

Folinic acid helps bypass folate receptor autoantibodies (FRAAs), restoring folate levels and supporting brain health in CFD and ASD. Learn more about its benefits.

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Neurodiversity & Wellbeing Why Testing for FRAAs with FRAT® is Important?
Neurodiversity & Wellbeing

Why Testing for FRAAs with FRAT® is Important?

Discover why testing for folate receptor autoantibodies (FRAAs) with FRAT® is crucial for diagnosing CFD, ASD, and guiding personalized treatment for better outcomes.

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Autism Spectrum Disorders – II (Comorbid Mental Health Problems) Demystifying Depression - The Biological Blue Prints Behind the Blues
Autism Spectrum Disorders – II (Comorbid Mental Health Problems)

Demystifying Depression: The Biological Blueprints Behind the Blues

Explore the biological roots of depression, from neurotransmitter pathways to the neuro-endocrine system, uncovering the science behind mood regulation.

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  • FRAT® (Folate Receptor Antibody Test) is a diagnostic blood test that screens for Folate Receptor Autoantibodies. Developed in the laboratory of Dr. Edward Quadros at the State University of New York (SUNY Downstate), FRAT® is the only assay that identifies BOTH blocking and binding Folate Receptor Autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world's leading assay of its kind.

    The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into the cerebrospinal fluid (CSF).

    Folate Receptor Autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Depression, Schizophrenia as well as other neuropsychiatric and neurodevelopmental disorders.

    Diagnosis of Folate Receptor Autoantibodies should be done as early as possible as this may affect treatment outcomes.

    Please consult your physician for further information.

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