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  • Autism (64)
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Why is Folinic Acid so Promising in a Subtype of Children with Autism?
Neurodiversity & Wellbeing

Why is Folinic Acid so Promising in a Subtype of Children with Autism?

Discover how folinic acid helps children with autism and FRAAs by restoring brain folate, improving speech, behavior, and communication.

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Folate and Vitamin B12 (In Health and Disease) Structure of Folic Acid - Pteroyl Monoglutamic Acid
Folate and Vitamin B12 (In Health and Disease)

Folate in Health and Disease: Biochemistry and Function of Folates

Explore the biochemistry and functions of folates in health and disease. Learn more about the importance of folate intake and its role in essential biological pathways.

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Neurodiversity & Wellbeing How do Folate Receptor Autoantibodies contribute to CFD?
Neurodiversity & Wellbeing

How do Folate Receptor Autoantibodies contribute to CFD?

Explore Cerebral Folate Deficiency Syndrome, where typical early development transitions to psychomotor regression due to disruptions in folate receptor function.

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Autism How is Autism Diagnosed?
Autism

How is Autism Diagnosed?

Learn more about the comprehensive process of diagnosing ASD, including initial screenings and supplemental tests.

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Neurodiversity & Wellbeing Folate, Infants, Toddlers, and Folate Receptor Autoantibodies
Neurodiversity & Wellbeing

How does Folate Deficiency in Infants and Toddlers relate to CFD and FRAAs?

Learn more about the importance of folate for infants and toddlers, its role in Cerebral Folate Deficiency, and treatment options.

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Autism Autism Meltdown - A Guide For Everyone
Autism

Autism Meltdown: A Guide For Everyone

Explore autism meltdown triggers, differences from tantrums, prevention strategies, and supportive tips for managing effectively.

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Neurodiversity & Wellbeing How Do Folate, Folic Acid, and L-methylfolate Differ in Pregnancy and Nutrition?
Neurodiversity & Wellbeing

How Do Folate, Folic Acid, and L-methylfolate Differ in Pregnancy and Nutrition?

Explore the intricacies of Vitamin B9 variants-folate, folic acid, and l-methylfolate and their crucial roles in pregnancy nutrition.

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Autism Navigating the Spectrum: The 3 Autism Levels Explained
Autism

Navigating the Spectrum: The 3 Autism Levels Explained

Discover the 3 autism levels and their impact on support needs within the Autism spectrum disorder (ASD) severity levels.

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Neurodiversity & Wellbeing Folate, FRAAs, FRAT® and Subfertility's Impact on Reproduction
Neurodiversity & Wellbeing

What is the link between Folate, Subfertility, Brain Development, ASD and FRAAs?

Discover the connection between folate, FRAT®, and subfertility. Explore the impact of FRAAs on reproduction & neurodevelopment.

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Neurodiversity & Wellbeing Folate's Role in Preventing Neural Tube Defects During Pregnancy
Neurodiversity & Wellbeing

How Does Folate Contribute to Preventing Neural Tube Defects in Pregnancy?

Explore the vital role of folate in preventing neural tube defects and its impact on pregnancy.

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Developmental Delays (In Infancy and Early Childhood) The structure of a eukaryotic cell alongside a human cell
Developmental Delays (In Infancy and Early Childhood)

Developmental Delays in Infancy and Early Childhood: Peroxisomal Disorders

Explore the complexities of peroxisomal disorders and their implications for developmental delays.

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Autism Understanding the What, Why and How of Autism Masking
Autism

Understanding the What, Why and How of Autism Masking

Explore what is autism masking, and the motivations behind it. Learn the benefits vs drawbacks of autism masking.

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Neurodiversity & Wellbeing Image illustrating Folate (Vitamin B9) as a Critical Nutrient for Humans
Neurodiversity & Wellbeing

How Does Folate (Vitamin B9) Impact Health, and What Influences Its Absorption and Use?

Discover the critical role of folate (Vitamin B9) in human health and why it’s essential for overall well-being.

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Developmental Delays (In Infancy and Early Childhood) Illustration depicting inborn errors of metabolism (IEMs), aminoacidopathies, phenylalanine, and tyrosine metabolism disorders, emphasizing essential amino acids.
Developmental Delays (In Infancy and Early Childhood)

Developmental Delays in Infancy and Early Childhood: Phenylalanine and Tyrosine Metabolism Disorders

Discover the impact of inherited metabolic disorders on childhood development. Learn about modes of inheritance, phenylketonuria (PKU), and amino acid metabolism.

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Neurodiversity & Wellbeing Illustration showing the impact of folinic acid supplementation and folate receptor autoantibodies on neurodevelopmental and autism spectrum disorders.
Neurodiversity & Wellbeing

How does folinic acid supplementation impact neurodevelopmental disorders?

Discover the impact of folinic acid on neurodevelopmental disorders and the significance of early detection of folate receptor autoantibodies.

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Autism Can Autism Go Away
Autism

Can Autism Go Away?

Learn why autism does not fade with age. Explore effective therapies, early intervention, and hope for managing symptoms and unlocking potential.

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  • FRAT® (Folate Receptor Antibody Test) is a diagnostic blood test that screens for Folate Receptor Autoantibodies. Developed in the laboratory of Dr. Edward Quadros at the State University of New York (SUNY Downstate), FRAT® is the only assay that identifies BOTH blocking and binding Folate Receptor Autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world's leading assay of its kind.

    The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into the cerebrospinal fluid (CSF).

    Folate Receptor Autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Depression, Schizophrenia as well as other neuropsychiatric and neurodevelopmental disorders.

    Diagnosis of Folate Receptor Autoantibodies should be done as early as possible as this may affect treatment outcomes.

    Please consult your physician for further information.

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