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  • Autism (64)
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Empirical use of Folinic Acid-Why Not Use!
Neurodiversity & Wellbeing

Empirical use of Folinic Acid-Why Not Use!

Discover why high-dose folinic acid should be reserved for FRAT®-positive cases and the importance of FRAT® testing in guiding safe, targeted therapy.

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Neurodiversity & Wellbeing Folate, Autism and Cerebral Folate Deficiency Syndrome
Neurodiversity & Wellbeing

Folate, Autism and Cerebral Folate Deficiency Syndrome

Cerebral Folate Deficiency Syndrome (CFDS), linked to autism, affects brain development due to low CSF folate levels. Learn more about symptoms, causes, and treatment options.

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Autism Understanding Autism in Girls vs Boys
Autism

Understanding Autism in Girls vs Boys

Learn why girls with autism are often underdiagnosed and explore the unique challenges they face. This blog explores the gender gap in autism diagnosis and the importance of recognizing diverse presentations.

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Neurodiversity & Wellbeing How Does Having a Child With Autism Affect Parenting?
Neurodiversity & Wellbeing

How Does Having a Child With Autism Affect Parenting?

Parenting a child with autism can be challenging and rewarding. Discover practical tips and guidance on understanding, support systems, therapy, communication, and more.

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Folate and Vitamin B12 (In Health and Disease) Folate Interconversions and Degradation
Folate and Vitamin B12 (In Health and Disease)

Folate in Health and Disease: Determination of Folate Vitamers in Serum, Whole Blood, and Cerebrospinal Fluid

Explore advanced methods for determining folate vitamers in serum, whole blood, and cerebrospinal fluid. Learn more about folate stability, interconversions, and accurate measurement techniques.

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Neurodiversity & Wellbeing Cerebral Folate Deficiency Syndrome – The Latest News
Neurodiversity & Wellbeing

Cerebral Folate Deficiency Syndrome – the latest News

Learn more about Cerebral Folate Deficiency Syndrome (CFDS) its symptoms, causes, diagnosis, and effective treatments to manage this neurological disorder.

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Autism Why ABA Therapy Doesn’t Work?
Autism

Why ABA Therapy Doesn’t Work?

Discover why ABA therapy might not work for everyone, exploring known limitations and emerging factors like cerebral folate deficiency affecting autism treatment.

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Neurodiversity & Wellbeing Making Friends with an Autistic Child
Neurodiversity & Wellbeing

Making Friends with an Autistic Child

Learn how parents can help their children befriend autistic children, fostering understanding and inclusivity in school-age friendships.

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Developmental Origins of Health and Disease (DOHaD) Epigenetic Remodeling in Embryogenesis
Developmental Origins of Health and Disease (DOHaD)

Developmental Origins of Health and Disease: Epigenetics, Nutrition, and Infant Health

Explore how epigenetics and nutrition impact infant health and development, influencing lifelong well-being through mechanisms like DNA methylation and histone modification.

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Neurodiversity & Wellbeing Folate Receptor Autoantibodies – Be Aware!
Neurodiversity & Wellbeing

Folate Receptor Autoantibodies – Be Aware !

Discover the impact of Folate Receptor Autoantibodies (FRαa) on health, affecting folate transport to the brain. Learn about diagnosis, treatment, and implications for neurodevelopmental disorders.

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Autism
Autism

Frequently Asked Questions on ADHD & Autism Overlap, Differences

Confused about ADHD and Autism? This blog clears up the confusion, explains the differences, and answers the most frequently asked questions on ADHD and Autism.

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Neurodiversity & Wellbeing What is the link between Brain Plasticity, Folate, and FRAAs?
Neurodiversity & Wellbeing

What is the link between Brain Plasticity, Folate, and FRAAs?

Discover how early brain plasticity influences cognition and the critical roles of folate and FRAAs in brain development. Learn about the FRAT® test for assessing folate receptor autoantibodies.

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Developmental Delays (In Infancy and Early Childhood) Tetrahydrofolate THF and Tetrahydrobiopterin-BH4
Developmental Delays (In Infancy and Early Childhood)

Developmental Delays in Infancy and Early Childhood: Biopterin and Folate Metabolism Interrelations

Uncover the link between biopterin and folate metabolism in developmental delays. Explore BH4 deficiency, its impact on neurotransmitters, and potential treatments for ASD and other conditions.

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Neurodiversity & Wellbeing Autism, Infertility, Developmental Delays: Can the FRAT® Test Help?
Neurodiversity & Wellbeing

FRAT® (Folate Receptor Autoantibody Test) and its Urgency.

Concerned about unexplained health issues in your child? Learn how the FRAT® Test can identify Folate deficiencies and support a personalized treatment plan.

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Autism Clothing Sensitivity in Autism
Autism

Clothing Sensitivity in Autism

Explore the reasons behind clothing sensitivity in autism and the impact it has on daily life. Discover strategies for creating a comfortable wardrobe and addressing public undressing.

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Neurodiversity & Wellbeing What is FRAT®?
Neurodiversity & Wellbeing

What is FRAT®?

FRAT® (Folate Receptor Autoantibody Test) detects autoantibodies against folate receptors, helping diagnose neurological disorders, pregnancy complications, and cerebral folate deficiency.

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  • FRAT® (Folate Receptor Antibody Test) is a diagnostic blood test that screens for Folate Receptor Autoantibodies. Developed in the laboratory of Dr. Edward Quadros at the State University of New York (SUNY Downstate), FRAT® is the only assay that identifies BOTH blocking and binding Folate Receptor Autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world's leading assay of its kind.

    The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into the cerebrospinal fluid (CSF).

    Folate Receptor Autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Depression, Schizophrenia as well as other neuropsychiatric and neurodevelopmental disorders.

    Diagnosis of Folate Receptor Autoantibodies should be done as early as possible as this may affect treatment outcomes.

    Please consult your physician for further information.

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