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  • Autism (66)
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Folate and Depression – What is the Connection?
Neurodiversity & Wellbeing

Folate and Depression – What is the Connection?

Discover how folate impacts brain function, neurotransmitters, and inflammation—uncover its powerful role in preventing and managing depression.

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Autism Interacting with a child who has autism
Autism

Interacting with a child who has autism

Interact with autistic children in a positive way by learning communication tips, respecting personal space, and supporting their emotional needs.

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Neurodiversity & Wellbeing The Role of Vitamins in Autism
Neurodiversity & Wellbeing

The Role of Vitamins in Autism

Explore the role of vitamins in autism, including potential benefits for cognitive function, behavior, immune health, and more. Learn about key vitamin supplements.

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Autism Frequently Asked Questions About Autism
Autism

Frequently Asked Questions About Autism

Get answers to common questions about autism, including signs, causes, diagnosis, and support options. Learn about autism’s complexities and the FRAT® test for early insights.

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Neurodiversity & Wellbeing Folic Acid and Autism
Neurodiversity & Wellbeing

Folic Acid and Autism

Explore folic acid’s benefits in preventing neural tube defects and its possible link to autism. Understand about Vitamin B9 and its impact on health and development

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Brain and Mind Development (First 5 Years of Life) Early Brain Wiring - Mapping Infant White Matter Connectivity
Brain and Mind Development (First 5 Years of Life)

Brain Plasticity – III: Fueling Brain Growth – The Vital Role of Nutrition During Sensitive Periods of Learning

Explore brain plasticity’s peak during early childhood, the critical role of nutrition, and how early intervention shapes lifelong cognitive and learning abilities.

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Neurodiversity & Wellbeing Folic Acid Folate Methylfolate
Neurodiversity & Wellbeing

Folic Acid, Folate, Methylfolate

Understand Vitamin B9 (Folate), its forms—Folic Acid, Folinic Acid, and 5-MTHF—their differences, benefits, and key roles in health, pregnancy, and cell function.

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Autism Social Deficits in Autism
Autism

Social Deficits in Autism

Social deficits in autism refer to challenges individuals with autism spectrum disorder (ASD) face in understanding, interpreting, and responding to social cues and information

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Neurodiversity & Wellbeing Folate Receptor Autoantibodies - Blocking vs Binding – What is the Difference?
Neurodiversity & Wellbeing

Folate Receptor Autoantibodies – Blocking vs Binding – What is the Difference?

Discover the difference between folate receptor blocking vs binding autoantibodies and their role in autism, cerebral folate deficiency, and neurodevelopmental disorders.

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Brain and Mind Development (First 5 Years of Life) But the Butterflies of the Brain (Neuronal Elegance Unveiled)
Brain and Mind Development (First 5 Years of Life)

Brain Plasticity – II: But the Butterflies of the Brain – Neuronal Elegance Unveiled

Explore the brain’s elegance with insights on neural plasticity, synapses, and disorders like autism and schizophrenia. Unlock the secrets of brain adaptability and function.

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Neurodiversity & Wellbeing PANS/PANDAS – Diagnosis and Possible Treatments
Neurodiversity & Wellbeing

PANS/PANDAS – Diagnosis and Possible Treatments

Folinic acid aids PANS/PANDAS treatment by bypassing folate receptor autoantibodies, improving brain function, and reducing neuropsychiatric symptoms.

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Autism Toe Walking in Autism
Autism

Toe Walking in Autism: Causes, Treatment, and Early Identification

Toe walking is when a child walks primarily on their toes instead of their entire foot. Toe walking is substantially higher in children with autism, ranging from 20% to 45%.

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Neurodiversity & Wellbeing Review of an Exciting Publication
Neurodiversity & Wellbeing

Review of an Exciting Publication

Explore the promising benefits of folinic acid for children with autism and folate receptor autoantibodies, improving communication and reducing core ASD symptoms.

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Autism Spectrum Disorders – I (Neurotypical Brain versus Autistic Brain) Synaptic Genes and Neurodevelopmental Disorders Regression in Autism
Autism Spectrum Disorders – I (Neurotypical Brain versus Autistic Brain)

Defining Autism Spectrum Disorders: Mechanisms of Developmental Regression in Autism – II

Explore the complex interplay between genetic factors, immune responses, and environmental triggers in developmental regression in autism. Learn about potential treatment strategies.

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Neurodiversity & Wellbeing College Scholarships for Autistic Students
Neurodiversity & Wellbeing

College Scholarships for Autistic Students

Discover scholarships for autistic students and tips on securing financial aid. Learn how to find autism-specific and general disability scholarships for college success.

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Autism What is missed autism diagnosis?
Autism

What is missed autism diagnosis?

Missed autism diagnosis refers to the failure to accurately identify autism spectrum disorder (ASD) in individuals who exhibit its characteristic symptoms. But why does this happen? Read our blog to know the answer.

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  • FRAT® (Folate Receptor Antibody Test) is a diagnostic blood test that screens for Folate Receptor Autoantibodies. Developed in the laboratory of Dr. Edward Quadros at the State University of New York (SUNY Downstate), FRAT® is the only assay that identifies BOTH blocking and binding Folate Receptor Autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world's leading assay of its kind.

    The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into the cerebrospinal fluid (CSF).

    Folate Receptor Autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Depression, Schizophrenia as well as other neuropsychiatric and neurodevelopmental disorders.

    Diagnosis of Folate Receptor Autoantibodies should be done as early as possible as this may affect treatment outcomes.

    Please consult your physician for further information.

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