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  • Autism (67)
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    • Autism Spectrum Disorders – I (Neurotypical Brain versus Autistic Brain) (8)
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Folate Blocking vs Binding Autoantibodies
Neurodiversity & Wellbeing

Folate Blocking vs Binding Autoantibodies

Learn how folate receptor blocking and binding autoantibodies disrupt folate transport, cause cerebral folate deficiency, and affect neurodevelopment.

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Autism Spectrum Disorders – II (Comorbid Mental Health Problems) Decoding Depression - Comprehensive Insights and Future Horizons
Autism Spectrum Disorders – II (Comorbid Mental Health Problems)

Decoding Depression: Comprehensive Insights and Future Horizons

Explore the evolution of depression treatment from ancient beliefs to modern therapies, including antidepressants, psychological treatments, and emerging innovations.

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Neurodiversity & Wellbeing Folate Receptor Autoantibodies and Depression
Neurodiversity & Wellbeing

Folate Receptor Autoantibodies and Depression

Discover how folate receptor autoantibodies (FRAAs) impact depression by blocking folate transport. Learn about testing & targeted treatments for mood disorders.

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Autism Savant Syndrome and Autism
Autism

Savant Syndrome and Autism

Explore the fascinating link between savant syndrome and autism. Discover how some individuals develop extraordinary talents despite developmental challenges.

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Neurodiversity & Wellbeing What is the Difference Between Folate, Folic Acid, Folinic Acid, and Methylfolate?
Neurodiversity & Wellbeing

What is the Difference Between Folate, Folic Acid, Folinic Acid, and Methylfolate?

Learn the key differences between folate, folic acid, folinic acid, and methylfolate—how they impact health, metabolism, and MTHFR mutations.

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Neurodiversity & Wellbeing Positive FRAT® Test: Steps to Take Now!
Neurodiversity & Wellbeing

Positive FRAT® Test: Steps to Take Now!

Discover what to do after a positive FRAT® test result, from consulting specialists to treatment options like folate supplementation and dietary changes.

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Autism Spectrum Disorders – II (Comorbid Mental Health Problems) The Folate Factor: Revealing the Hidden Impact on Depression
Autism Spectrum Disorders – II (Comorbid Mental Health Problems)

The Folate Factor: Revealing the Hidden Impact on Depression

Learn how folate impacts mental health and why its deficiency can worsen depression. Explore the benefits of supplementation for better mental well-being.

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Neurodiversity & Wellbeing Diet, Dairy and Folate Receptor Autoantibodies
Neurodiversity & Wellbeing

Diet, Dairy and Folate Receptor Autoantibodies

Learn how dairy consumption and folate receptor autoantibodies (FRAs) impact folate transport, neurological health, ASD, and the benefits of a dairy-free diet.

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Autism Hyperlexia and Autism
Autism

Hyperlexia and Autism

Explore the link between hyperlexia and autism, its signs, challenges, and the role of folate deficiency in early intervention for optimal child development.

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Neurodiversity & Wellbeing Folate Receptor Autoantibodies and Their Impact on Health and Relation to ASD
Neurodiversity & Wellbeing

Folate Receptor Autoantibodies: Their impact on Health and relation to ASD

Learn more about folate receptor autoantibodies, their impact on health, and their potential link to autism spectrum disorder (ASD) and treatment with folinic acid.

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Nutrition (In Health and Disease) Nutritional Epigenomics - Revolutionizing Brain Health and Cognitive Excellence
Nutrition (In Health and Disease)

Nutritional Epigenomics: Revolutionizing Brain Health and Cognitive Excellence

Discover the transformative power of nutritional epigenomics in optimizing brain health and cognitive function. Learn how diet influences gene expression to enhance mental well-being.

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Neurodiversity & Wellbeing Why Your Physician Should Know FRAT®?
Neurodiversity & Wellbeing

Why Your Physician Should Know FRAT®?

Discover why physicians should be aware of the FRAT® test for detecting folate receptor autoantibodies linked to neurodevelopmental disorders like autism.

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Autism Autism Parenting Journey
Autism

Autism Parenting Journey

Learn how to support your autistic child with acceptance, FRAT® testing, tailored therapies, and early intervention strategies for lasting development.

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Neurodiversity & Wellbeing Folate Deficiency - Symptoms
Neurodiversity & Wellbeing

Folate Deficiency – Symptoms

Learn more about folate deficiency symptoms, causes, and treatment, including the role of folate receptor autoantibodies and the benefits of folinic acid therapy.

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First 1000 Days (From Conception to 2 years of Age) Methylation Cycle The One-Carbon Cycle
First 1000 Days (From Conception to 2 years of Age)

Mastering Methylation: Unlocking the Secrets of Health and Behavior

Discover how methylation impacts health and behavior. Learn about the one-carbon cycle, methylation disorders, epigenetics, and lab testing in this guide.

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Neurodiversity & Wellbeing FRAT® - What is it?
Neurodiversity & Wellbeing

FRAT® – What is it?

Explore FRAT®, a test identifying folate receptor autoantibodies, crucial for diagnosing cerebral folate deficiency and related neurological conditions.

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  • FRAT® (Folate Receptor Antibody Test) is a diagnostic blood test that screens for Folate Receptor Autoantibodies. Developed in the laboratory of Dr. Edward Quadros at the State University of New York (SUNY Downstate), FRAT® is the only assay that identifies BOTH blocking and binding Folate Receptor Autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world's leading assay of its kind.

    The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into the cerebrospinal fluid (CSF).

    Folate Receptor Autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Depression, Schizophrenia as well as other neuropsychiatric and neurodevelopmental disorders.

    Diagnosis of Folate Receptor Autoantibodies should be done as early as possible as this may affect treatment outcomes.

    Please consult your physician for further information.

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