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  • Autism (69)
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  • FRAT (1)
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    • Autism Spectrum Disorders – I (Neurotypical Brain versus Autistic Brain) (8)
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FRAAs, Subfertility, and Miscarriages
Neurodiversity & Wellbeing

FRAAs, Subfertility, and Miscarriages

Learn about folate receptor autoantibodies (FRAAs), their role in subfertility, miscarriages, and potential treatments like folinic acid and methylfolate.

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Autism This image depicts examples of hyper- sensitivity and hypo-sensitivity in autistic kids.
Autism

Sensory Issues and Autism: An all you need to know guide for parents & caregivers

It’s Saturday morning, and the first thing on David’s to-do list for the weekend is to vacuum the house…

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Autism Spectrum Disorders – I (Neurotypical Brain versus Autistic Brain) external view showing the lobes of the-brain
Autism Spectrum Disorders – I (Neurotypical Brain versus Autistic Brain)

The Neurotypical Brain versus the Autistic Brain: Neurotypical Brain Structure

Figure 1. Atypical Pattern of Connectivity in Autism Spectrum Disorder (ASD)…

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Autism Infographic representing difference between autism tests vs tests for other disorders
Autism

Decoding Autism: Essential Tests and Key Indicators You Can’t Afford to Ignore

Welcome to your guide to understanding autism tests. If you suspect…

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Folate and Vitamin B12 (In Health and Disease) intestinal absorption of dietary folates
Folate and Vitamin B12 (In Health and Disease)

Intestinal Absorption of Dietary Folates

Intestinal absorption of dietary folates is an important, complex, and fascinating process in human metabolism…

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Diagnosis & Therapy cerebral folate deficiency syndrome
Diagnosis & Therapy

Cerebral Folate Deficiency Syndrome

Cerebral folate deficiency syndrome (CFDS) is defined as any neuropsychiatric or developmental disorder characterized

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Autism education and employment opportunities for people with autism
Autism

Education and Employment Opportunities for People with Autism

If you or a loved one have autism, you may be wondering what options are available for education and employment…

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Folate and Vitamin B12 (In Health and Disease) folate transport systems folate receptors
Folate and Vitamin B12 (In Health and Disease)

Folate Transport Systems – II: Folate Receptors

Figure 1. Major Folate Transporters – the processes that regulate transmembrane folate flows and gradients. Folate transporters…

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Autism parenting strategies for children with autism
Autism

Parenting Strategies for Children with Autism

As a parent of a child with autism, you know that parenting strategies can make a world of difference in your child’s development and overall well-being…

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Folate and Vitamin B12 (In Health and Disease) folate transport systems transmembrane carriers
Folate and Vitamin B12 (In Health and Disease)

Folate Transport Systems – I: Transmembrane Carriers

Folate transport by mammalian tissues and cells has been under intense scrutiny and the subject of several research studies [1-2]…

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Autism the folate factor in autism understanding the link between folate and autism spectrum disorder
Autism

The Folate Factor in Autism: Understanding the Link between Folate and Autism Spectrum Disorder

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder…

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Autism insurance coverage for autism
Autism

Insurance Coverage for Autism

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition that impacts communication, social interaction, and behavior…

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Autism new research findings on autism
Autism

New research findings on Autism

Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects an estimated 1 in 36 children in the United States (CDC, 2023)…

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Autism the rise of autism in the last two decades
Autism

The rise of Autism in the last two decades

Autism is a neurological disorder that affects social communication, behavior, and cognitive abilities…

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Autism Importance of Vitamin B9 (Folate) for Better Brain Development in Fetuses
Autism

Importance of Vitamin B9 (Folate) for Better Brain Development in Fetuses

Here are some of the reasons why vitamin B9 folate is crucial for better brain development in fetuses.

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Diagnosis & Therapy Cerebral Folate Deficiency – An Overview
Diagnosis & Therapy

Cerebral Folate Deficiency – An Overview

A family in the UK was devastated when their new-born son began to experience seizures and other developmental delays…

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  • FRAT® (Folate Receptor Antibody Test) is a diagnostic blood test that screens for Folate Receptor Autoantibodies. Developed in the laboratory of Dr. Edward Quadros at the State University of New York (SUNY Downstate), FRAT® is the only assay that identifies BOTH blocking and binding Folate Receptor Autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world's leading assay of its kind.

    The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into the cerebrospinal fluid (CSF).

    Folate Receptor Autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Depression, Schizophrenia as well as other neuropsychiatric and neurodevelopmental disorders.

    Diagnosis of Folate Receptor Autoantibodies should be done as early as possible as this may affect treatment outcomes.

    Please consult your physician for further information.

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