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The History of the FRAT® Test
Neurodiversity & Wellbeing

The History of the FRAT® Test

Discover the FRAT® test—an advanced diagnostic for folate receptor autoantibodies linked to autism, NTDs, and neurodevelopmental disorders.

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Autism What role does Folate Receptors and Vitamin B9 play in Autism?
Autism

What role does Folate Receptors and Vitamin B9 play in Autism?

Folate is a B-vitamin that is essential for proper brain development and function, and it is involved in the synthesis of neurotransmitters and DNA.

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Autism What has Autism taught me as a parent?
Autism

What has Autism taught me as a parent?

Discover heartfelt lessons from parenting a child with autism—appreciating small wins, embracing patience, and learning to advocate with love.

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Autism How do I know my child may be on the Autism Spectrum?
Autism

How do I know my child may be on the Autism Spectrum?

Worried your child may have autism? Discover 7 early signs of Autism Spectrum Disorder every parent should know to seek timely support and diagnosis.

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Autism Activities to Do with Your Autistic Children
Autism

Activities to Do with Your Autistic Children

Discover 7 fun and engaging activities to enjoy with your autistic child, from swimming to painting, all designed to boost bonding and support development.

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Autism Advice for Parents with Autistic Children
Autism

Advice for Parents with Autistic Children

Essential parenting tips for raising autistic children with love, structure, and support. Learn how to create a nurturing, calm, and communicative environment.

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Autism What is FRAT® and the role FRAT® plays in Autism
Autism

What is FRAT® and the role FRAT® plays in Autism

Discover FRAT®, a patented test that detects folate receptor antibodies linked to autism. Early testing helps manage ASD.

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Autism A Comprehensive Introduction to Autism Spectrum Disorder
Autism

A Comprehensive Introduction to Autism Spectrum Disorder

ASD is a developmental disease that affects the brain cells and leads to find hardness in communication, interpreting what others are thinking, and social behavior.

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  • FRAT® (Folate Receptor Antibody Test) is a diagnostic blood test that screens for Folate Receptor Autoantibodies. Developed in the laboratory of Dr. Edward Quadros at the State University of New York (SUNY Downstate), FRAT® is the only assay that identifies BOTH blocking and binding Folate Receptor Autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world's leading assay of its kind.

    The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into the cerebrospinal fluid (CSF).

    Folate Receptor Autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Depression, Schizophrenia as well as other neuropsychiatric and neurodevelopmental disorders.

    Diagnosis of Folate Receptor Autoantibodies should be done as early as possible as this may affect treatment outcomes.

    Please consult your physician for further information.

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