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Folate Receptor Autoantibodies and Miscarriages
Neurodiversity & Wellbeing

Folate Receptor Autoantibodies and Miscarriages

Folate receptor autoantibodies may cause miscarriages by blocking folate transport. Learn about testing, treatment, and their role in pregnancy loss.

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Neurodiversity & Wellbeing Folate's Role in Preventing Neural Tube Defects During Pregnancy
Neurodiversity & Wellbeing

How Does Folate Contribute to Preventing Neural Tube Defects in Pregnancy?

Explore the vital role of folate in preventing neural tube defects and its impact on pregnancy.

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Developmental Delays (In Infancy and Early Childhood) The structure of a eukaryotic cell alongside a human cell
Developmental Delays (In Infancy and Early Childhood)

Developmental Delays in Infancy and Early Childhood: Peroxisomal Disorders

Explore the complexities of peroxisomal disorders and their implications for developmental delays.

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Autism Understanding the What, Why and How of Autism Masking
Autism

Understanding the What, Why and How of Autism Masking

Explore what is autism masking, and the motivations behind it. Learn the benefits vs drawbacks of autism masking.

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Neurodiversity & Wellbeing Image illustrating Folate (Vitamin B9) as a Critical Nutrient for Humans
Neurodiversity & Wellbeing

How Does Folate (Vitamin B9) Impact Health, and What Influences Its Absorption and Use?

Discover the critical role of folate (Vitamin B9) in human health and why it’s essential for overall well-being.

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Developmental Delays (In Infancy and Early Childhood) Illustration depicting inborn errors of metabolism (IEMs), aminoacidopathies, phenylalanine, and tyrosine metabolism disorders, emphasizing essential amino acids.
Developmental Delays (In Infancy and Early Childhood)

Developmental Delays in Infancy and Early Childhood: Phenylalanine and Tyrosine Metabolism Disorders

Discover the impact of inherited metabolic disorders on childhood development. Learn about modes of inheritance, phenylketonuria (PKU), and amino acid metabolism.

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Neurodiversity & Wellbeing Illustration showing the impact of folinic acid supplementation and folate receptor autoantibodies on neurodevelopmental and autism spectrum disorders.
Neurodiversity & Wellbeing

How does folinic acid supplementation impact neurodevelopmental disorders?

Discover the impact of folinic acid on neurodevelopmental disorders and the significance of early detection of folate receptor autoantibodies.

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Autism Can Autism Go Away
Autism

Can Autism Go Away?

Learn why autism does not fade with age. Explore effective therapies, early intervention, and hope for managing symptoms and unlocking potential.

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Developmental Delays (In Infancy and Early Childhood) Diagram illustrating organic aciduria in branched-chain amino acid metabolism, β-oxidation of odd-chain fatty acids, and a general schematic of a metabolic pathway.
Developmental Delays (In Infancy and Early Childhood)

Developmental Delays in Infancy and Early Childhood: Branched-Chain Amino Acid and Organic Acid Metabolism Disorders

Discover the intricacies of early childhood developmental delays related to amino acid and organic acid disorders.

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Neurodiversity & Wellbeing Image depicting the impact of folate receptor autoantibodies on health and the role of folinic acid in treatment - Understanding the link between autoimmune response and folate deficiency.
Neurodiversity & Wellbeing

How do folate receptor autoantibodies affect health, and how is folinic acid used in treatment?

Folate receptor autoantibodies are antibodies produced by the immune system that target folate receptor alpha in the body. Folate receptors are proteins located on the surface of cells and are responsible for facilitating the transport and uptake of folate (vitamin B9) into cells.

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Autism Child with Speech Development Milestones: Attempts Words like 'ba' for ball and 'da' for dog - Autism and Speech Delay Awareness
Autism

A Guide to Speech Delay and Autism: Types, Red Flags, Impact and the Power of Early Intervention

Speech delay in autism involves difficulties with communication skills, particularly spoken language, compared to developmental expectations for a child’s age.

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Autism Child demonstrating echolalia, repeating words, a common communication trait in individuals affected by the condition.
Autism

Echolalia in Autism: Causes, Types, Reasons, Treatment and Support

Echolalia basically means non-voluntary repetition of another individual’s speech. Sometimes it can sound automatic or even robotic, especially in children learning to speak.

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Developmental Delays (In Infancy and Early Childhood) Diagram illustrating the two pathways of homocysteine metabolism: folate-dependent and folate-independent.
Developmental Delays (In Infancy and Early Childhood)

Developmental Delays in Infancy and Early Childhood: Metabolism of Homocysteine

Learn about developmental delays in infancy and early childhood linked to homocysteine metabolism.

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Neurodiversity & Wellbeing Folate and Brain Development - Illustration depicting the role of folate in promoting healthy brain development.
Neurodiversity & Wellbeing

The Role of Folate in Brain Development: Why It Matters and How it Could Impact Autism

Explore the crucial link between folate and brain development, and its potential impact on autism spectrum disorders.

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Autism A girl with blonde hair sleeps serenely on a white bed, her soft toy nestled beside her.
Autism

Understanding and Managing Sleep Problems in Children with ASD

The Holidays are upon us! And as such, if we are lucky, we will have a few days off to celebrate.

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Autism
Autism

From Triggers to Strategies: Understanding and Navigating Autism Wandering

In December 2017, four-year-old Chelsea Noel residing in Port St. Lucie embarked on a journey her family never anticipated.

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  • FRAT® (Folate Receptor Antibody Test) is a diagnostic blood test that screens for Folate Receptor Autoantibodies. Developed in the laboratory of Dr. Edward Quadros at the State University of New York (SUNY Downstate), FRAT® is the only assay that identifies BOTH blocking and binding Folate Receptor Autoantibodies. FRAT®, as published in the New England Journal of Medicine, and used in numerous clinical trials, is the world's leading assay of its kind.

    The presence of Folate Receptor Autoantibodies suggests that folate (vitamin B9), which is an essential vitamin for proper growth and neurological function, is not being properly transported to the brain and into the cerebrospinal fluid (CSF).

    Folate Receptor Autoantibodies have been found in Cerebral Folate Deficiency Syndrome, Autism Spectrum Disorders, Depression, Schizophrenia as well as other neuropsychiatric and neurodevelopmental disorders.

    Diagnosis of Folate Receptor Autoantibodies should be done as early as possible as this may affect treatment outcomes.

    Please consult your physician for further information.

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