FRAT® testing prior to leucovorin therapy ensures accurate diagnosis, personalized dosing, and better outcomes in cerebral folate deficiency and ASD.
Rising autism prevalence and the FDA approval of leucovorin highlight a targeted metabolic approach for ASD linked to cerebral folate deficiency.
Leucovorin demand is rising in ASD care. Learn why folic acid is not an alternative and may worsen cerebral folate deficiency.
Learn how FRAT® helps explain unexplained autism symptoms by detecting folate receptor autoantibodies affecting the brain.
FRAT® testing before folinic acid therapy identifies folate receptor autoantibodies, enabling precise, effective treatment for cerebral folate deficiency and autism.
Explore the science linking cerebral folate deficiency syndrome (CFDS) and autism spectrum disorder, including mechanisms, testing, and folinic acid therapy.
Understand the impact of Christmas on autistic individuals and families, with expert tips to reduce anxiety and create a joyful, inclusive season.
Learn why leucovorin may be more effective for those with folate receptor autoantibodies and how it helps bypass blocked folate pathways.
Discover why early FRAT® testing is vital for your child’s brain development and how timely detection of FRAAs can prevent lifelong neurological challenges.
Discover how folate receptor autoantibodies contribute to cerebral folate deficiency and a distinct autism subgroup, including prevalence, mechanisms, and treatment.









