Learn how FRα autoantibodies impair folate transport across the BBB, causing cerebral folate deficiency and impacting brain development and function.
Early FRAT® testing detects folate receptor autoantibodies, enabling timely treatment to prevent neurological damage and improve outcomes in autism and related disorders.
Learn about Pathological Demand Avoidance (PDA) in autism—key signs, causes, and practical strategies to support individuals and reduce daily challenges.
New Swedish research reveals why autism diagnoses differ between males and females and how awareness is closing the gender gap in autism spectrum disorder.
A new autism theory links symptoms to brain energy deficits. Discover how impaired glucose metabolism may affect behavior, speech, and sensory processing.
Leucovorin may help ASD with FRAAs by bypassing blocked folate transport to the brain. Learn how folinic acid supports communication and treats cerebral folate deficiency.
FRAT® test detects folate receptor autoantibodies linked to autism, cerebral folate deficiency, and NTDs—enabling early diagnosis and targeted folinic acid treatment.
Explore how folate receptor alpha autoantibodies (FRAAs) disrupt brain folate transport and contribute to autism spectrum disorder, cerebral folate deficiency, and targeted treatment insights.
FRAT® testing prior to leucovorin therapy ensures accurate diagnosis, personalized dosing, and better outcomes in cerebral folate deficiency and ASD.
Rising autism prevalence and the FDA approval of leucovorin highlight a targeted metabolic approach for ASD linked to cerebral folate deficiency.